Extradural multiple spinal meningioma. Literature review a case report
Related Experiment Videos
Abstract:
A case is reported of recurring or multiple spinal meningioma and focuses again on the incomplete information at present available regarding this class of meningioma. Repeated operations were performed earlier in the extradural space at C2 and an intradural tumour at the same level was completely removed. After a six year interval, we diagnosed an intramedullary meningioma once again at C2, which was subtotally removed. Histological examination indicated an angioblastic tumour, the same type of meningioma as was previously found. Postoperative recovery was satisfactory. Two years later, an intradural extramedullary tumour at T2-3 level was totally removed. Again postoperative recovery went well. In view of the rare occurrence of this meningioma, and the reports on it, we envisaged the pathogenesis of our case as an invasion from the extradural into the intradural space and into the spinal cord. Its appearance in the thoracic region might have been by dissemination via the cerebrospinal fluid pathways or it may have occurred independently.
Insights
This case study details recurring spinal meningiomas, highlighting the challenges in understanding these rare tumors. Multiple surgeries were required to manage the angioblastic meningioma at different spinal levels.
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Spinal meningiomas are rare tumors, with multiple or recurrent instances presenting unique diagnostic and therapeutic challenges.
- Understanding the pathogenesis of spinal meningiomas, particularly angioblastic subtypes, is crucial for effective management.
Observation:
- A patient presented with a history of multiple spinal meningiomas requiring repeated surgical interventions at C2 and T2-3 levels.
- Initial operations involved extradural and intradural tumors at C2, followed by an intramedullary meningioma at the same level six years later.
- A subsequent intradural extramedullary tumor at T2-3 was also surgically removed, with satisfactory postoperative recovery in all instances.
Findings:
- Histological examination confirmed an angioblastic meningioma, consistent with previous diagnoses.
- The recurring nature and varied locations (extradural, intradural, intramedullary) suggest complex growth patterns.
Implications:
- The case suggests potential pathogenesis involving invasion from extradural to intradural spaces and the spinal cord.
- Dissemination via cerebrospinal fluid pathways or independent occurrence are considered for thoracic region recurrence.
- Further research is needed to elucidate the mechanisms behind multiple and recurrent spinal meningiomas.