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Bactericidal Activity of Superabsorbent Polymer Granules for Their Applications in Respiratory Fluid Solidification
Manju Saraswathy1, Manoj Komath2, Deepu Damodharan Ragini1
1Department of Biomaterial Science and Technology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum 695012, India.
ACS Omega
|July 24, 2023
Summary
AcryloSorb canister liner bags safely solidify and disinfect contagious respiratory secretions. Disinfectant-impregnated superabsorbent polymer (DSAP) granules, particularly DSAP-S5, offer effective bactericidal activity and maintain granule integrity for healthcare safety.
Area of Science:
- Infection Control and Prevention
- Materials Science
- Microbiology
Background:
- Disposal of respiratory secretions from contagious diseases poses infection risks to healthcare workers.
- AcryloSorb canister liner bags offer a solution for safe handling through solidification and disinfection.
- These bags utilize disinfectant-impregnated superabsorbent polymer (DSAP) granules with a patented design for enhanced absorption.
Purpose of the Study:
- To evaluate the bactericidal efficacy of DSAP granules against Gram-negative (Klebsiella pneumoniae) and Gram-positive (MRSA) bacteria.
- To assess the solidification capacity of DSAP granules.
- To determine the optimal disinfectant-SAP formulation for AcryloSorb canister liner bags.
Main Methods:
- DSAP granules were prepared by impregnating superabsorbent polymer (SAP) with various disinfectants, including peracetic acid and sodium dichloroisocyanurate.
- Bactericidal activity was tested against Klebsiella pneumoniae and methicillin-resistant Staphylococcus aureus (MRSA).
- Solidification capacity and the effect of disinfectants on SAP granule morphology were evaluated.
Main Results:
- Peracetic acid-impregnated SAP (DSAP-P) showed 100% bactericidal activity at 0.5 wt% against both bacteria but caused SAP granule collapse.
- Sodium dichloroisocyanurate-impregnated SAP (DSAP-S5) demonstrated 100% bactericidal activity at 5 wt% and preserved SAP granule morphology.
- Different disinfectants exhibited varying bactericidal activities and impacts on SAP structure.
Conclusions:
- DSAP-S5 is a suitable candidate for AcryloSorb canister liner bags due to its effective disinfection, solidification, and preservation of SAP granule morphology.
- The study highlights the importance of balancing disinfectant efficacy with material stability for safe medical waste management.
- AcryloSorb technology provides a promising approach to mitigate infection risks associated with handling infectious respiratory secretions.
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