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Off-clamp robotic-assisted partial nephrectomy: surgical experience from a single centre.
Matteo Zanoni1, Fabio Grizzi2,3, Paolo Vota1
1Department of Urology, Humanitas Mater Domini, Castellanza, Varese, Italy.
Central European Journal of Urology
|July 24, 2023
Summary
Off-clamp robot-assisted partial nephrectomy (RAPN) is a safe and feasible technique for small renal tumors. This study found minimal intraoperative complications, with a low rate of post-operative hemorrhage and positive margins in 287 patients.
Area of Science:
- Urology
- Minimally Invasive Surgery
- Oncology
Background:
- Robot-assisted partial nephrectomy (RAPN) is a minimally invasive approach for localized renal tumors.
- Extended warm ischaemic time and complications can occur with traditional RAPN.
Purpose of the Study:
- To evaluate the surgical outcomes of off-clamp sutureless RAPN.
- To assess feasibility, positive margins, and complications associated with this technique.
Main Methods:
- A single centre performed off-clamp sutureless RAPN on 287 patients from January 2011 to November 2022.
- Data collected included patient characteristics, tumour features (PADUA, RENAL score), intraoperative details, and postoperative complications (Clavien-Dindo).
Main Results:
- No intraoperative complications were observed in 287 patients.
- 4 patients (1.4%) experienced post-operative hemorrhage requiring laparotomy (Clavien-Dindo stage IIIB).
- 4 patients (1.4%) had positive surgical margins.
Conclusions:
- Off-clamp selective arterial clamping during RAPN is safe and feasible for small renal tumors.
- Further randomized trials are needed to confirm renal functional benefits and reduced complications of RAPN without clamping.

