Advances in endobariatrics: past, present, and future.

Area of Science:

• Medical Science
• Gastroenterology
• Endoscopy

Background:

• The global obesity epidemic presents a significant public health challenge.
• Surgical bariatric procedures are effective but invasive.
• There is a growing need for less invasive therapeutic options.

Purpose of the Study:

• To review the evolution and current status of bariatric and metabolic endoscopy.
• To highlight recent advances and emerging technologies in endobariatrics.
• To discuss future directions in endoscopic weight management.

Main Methods:

• Comprehensive review of literature on endobariatric therapies over several decades.
• Description of Food and Drug Administration-cleared devices.
• Summary of interventions currently under investigation.

Main Results:

• Overview of various endoscopic interventions including gastric devices, gastric remodeling, and small-bowel devices.
• Discussion of duodenal ablation techniques.
• Exploration of endoscopic solutions for weight regain after bariatric surgery.

Conclusions:

• Endoscopic therapies represent a rapidly advancing field in obesity management.
• Future research will focus on combination therapies, pharmacotherapy, and personalized approaches.
• Endobariatrics offers a promising, less invasive alternative for managing obesity.