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Squawks as an important physical finding for differentiation of diffuse panbronchiolitis from asthma in children: A

Hisatoshi Okumura1, Atsushi Kawashima1, Akiko Hanamoto2

  • 1Division of General Internal Medicine Fukuchiyama City Hospital Fukuchiyama-shi Japan.

Journal of General and Family Medicine
|July 24, 2023
PubMed

Insights

Diffuse panbronchiolitis (DPB) is a chronic lung disease often misdiagnosed in children. Early diagnosis and macrolide antibiotic treatment significantly improve quality of life for young patients.

Area of Science:

  • Pulmonology
  • Pediatric Respiratory Medicine

Background:

  • Diffuse panbronchiolitis (DPB) is a rare idiopathic chronic inflammatory lung disease.
  • It typically affects adults but can occur in children, often misdiagnosed as asthma.

Observation:

  • A 16-year-old male, previously treated for asthma, presented with symptoms suggestive of DPB.
  • Key clinical signs included characteristic lung auscultation findings ('squawks') and a history of purulent sputum.

Findings:

  • The patient received a correct diagnosis of DPB based on clinical evaluation.
  • Initiation of long-term macrolide antibiotic therapy was implemented.

Implications:

  • This case highlights the importance of considering DPB in pediatric patients with persistent respiratory symptoms misdiagnosed as asthma.
  • Timely diagnosis and appropriate macrolide treatment can significantly improve patient outcomes and quality of life in young DPB patients.

Keywords:
asthmadiffuse panbronchiolitissquawk

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