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Predictors of Non-Adherence to Medications in Hypertensive Patients

Aleksandra Nikolic1, Sonja Djuric2, Vladimir Biocanin3

  • 1Clinic for Rheumatology, Allergology and Clinical Immunology, Clinical Centre Kragujevac, Kragujevac, Serbia.

Iranian Journal of Public Health
|July 24, 2023
PubMed

Insights

High blood pressure medication adherence is challenging. Key predictors of non-adherence in hypertensive patients include taking multiple medications, living in urban areas, forgetfulness, and low energy levels.

Area of Science:

  • Cardiology
  • Public Health
  • Pharmacology

Background:

  • Hypertension is a leading cause of cardiovascular events globally.
  • Poor medication adherence is a significant public health concern.
  • Understanding adherence predictors is crucial for effective hypertension management.

Purpose of the Study:

  • To identify predictors of poor medication adherence in hypertensive patients in Serbia.
  • To analyze factors influencing adherence to antihypertensive therapy.

Main Methods:

  • An observational, analytical study involving 388 hypertensive patients.
  • Data collected via a self-developed questionnaire and the SF-36 quality of life survey.
  • A case-control study design was employed to assess variable influence.

Main Results:

  • Four independent predictors of non-adherence were identified: increased medication count, urban living, forgetfulness, and low energy.
  • Living in a city was associated with the highest odds of non-adherence.
  • Low energy was the only factor inversely associated with non-adherence levels.

Conclusions:

  • Multiple factors are associated with medication non-adherence in hypertensive patients.
  • Increased medication burden, urban residence, forgetfulness, and low energy are significant risk factors.
  • Further research is needed to develop optimal adherence promotion protocols.
Abstract

Keywords:
AdherenceHypertensionQuestionnaireRisk factors

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