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Enhanced extraction of phenolic compounds from mango by-products using deep eutectic solvents
Gonzalo A Ojeda1, Margarita M Vallejos1, Sonia C Sgroppo1
1Instituto de Química Básica y Aplicada del Nordeste Argentino (IQUIBA-NEA-CONICET), Universidad Nacional del Nordeste (UNNE), Av. Libertad 5400, Corrientes, Argentina.
Heliyon
|July 24, 2023
Summary
Deep eutectic solvents (DESs) efficiently extract polyphenolic compounds from mango by-products. These novel solvents significantly enhance extraction yields from mango peel and seed, offering a sustainable approach.
Area of Science:
- Green Chemistry
- Food Chemistry
- Biotechnology
Background:
- Mango by-products, including peel and seed, are rich sources of polyphenolic compounds (PC).
- Traditional extraction methods often use harsh solvents and have limited efficiency.
- Deep eutectic solvents (DESs) offer a promising alternative for sustainable extraction.
Purpose of the Study:
- To evaluate the potential of DESs for extracting polyphenolic compounds from mango peel and seed.
- To compare the efficacy of different DES formulations and extraction techniques (ultrasound vs. agitation).
- To characterize the extracted compounds and understand the underlying interactions between DES and polyphenols.
Main Methods:
- Extraction of polyphenolic compounds using various DES formulations and conventional solvents (ethanol/methanol).
- Application of ultrasound (US) and agitation as extraction methodologies.
- Characterization of extracts using antioxidant capacity assays and High-Performance Liquid Chromatography with Diode-Array Detection (HPLC-DAD).
- Theoretical analysis using density functional theory (DFT) and the Quantum Theory of Atoms in Molecules (QTAIM) approach.
Main Results:
- β-alanine and choline chloride-based DESs demonstrated high efficiency in extracting PC from both mango peel and seed.
- DESs significantly increased PC extraction yields, up to three times for peel and five times for seeds, compared to conventional solvents.
- Mangiferin extraction from mango peels was notably enhanced using β-alanine based DES.
- The study identified a correlation between hydrogen bond strength, DES viscosity, and extraction efficiency.
- Solute-solvent solvation energy proved effective in estimating DES-polyphenol interactions.
Conclusions:
- DESs exhibit remarkable capacity for extracting valuable polyphenolic compounds from mango by-products.
- The choice of DES and extraction method significantly influences the yield and profile of extracted PC.
- This research provides valuable insights into the application of DESs for sustainable valorization of agro-industrial waste.
