Related Experiment Video
Updated: Jul 22, 2025
07:03
Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
Published on: February 15, 2022
1.5K
A 55-Year-Old Male With Systemic Gout Complicated by Septic Shock
Jay E Garza1, Quoc-Bao Nguyen1, Daniel V Wang2
1Dermatology, McGovern Medical School, Houston, USA.
Cureus
|July 24, 2023
Summary
Chronic tophaceous gout can lead to severe infections. This case highlights a patient with gout experiencing septic shock from Staphylococcus aureus bacteremia and joint superinfections, emphasizing preventative care strategies.
Area of Science:
- Rheumatology
- Infectious Diseases
- Dermatology
Background:
- Tophaceous gout involves uric acid deposition, potentially causing skin ulcerations.
- Chronic gout management is crucial for preventing systemic complications.
Observation:
- A 55-year-old male with chronic tophaceous gout presented with severe complications.
- The patient developed septic shock due to methicillin-sensitive Staphylococcus aureus bacteremia.
Findings:
- Superinfection of multiple gouty joints occurred.
- The case illustrates a severe manifestation of infection in tophaceous gout.
Implications:
- Highlights the critical need for vigilant infection monitoring in tophaceous gout patients.
- Underscores the importance of preventative care to avoid severe outcomes like septic shock.
- Suggests a multidisciplinary approach for managing complex cases of tophaceous gout with infection.
Related Concept Videos
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
17
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
17
01:27Acute Pyelonephritis I: Introduction
23
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
23
01:29Acute Kidney Injury III: Clinical Manifestations
37
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
37
01:29Acute Kidney Injury II: Pathophysiology
34
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
34
01:22Acute Kidney Injury VI: Nursing Management
34
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
34
01:26Nephrotic Syndrome II : Assessment and Medical Management
8
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
8