Large Chorioangioma in Triplets: An Uncommon Occurrence

Area of Science:

• Obstetrics and Gynecology
• Maternal-Fetal Medicine
• Pathology

Background:

• A 25-year-old primigravida at 26 weeks gestation presented for routine antenatal care.
• No prior history of pregnancy-induced hypertension (PIH) or edema was noted.

Observation:

• Physical examination revealed pallor and microcytic hypochromic anemia.
• Elevated beta-human chorionic gonadotropin (HCG) and alpha-fetoprotein (AFP) levels were detected.
• Ultrasound showed triplets with intertwining membranes, and the placenta had a large, hypoechoic mass with a central feeding vessel.

Findings:

• The anomaly scan showed no fetal abnormalities.
• Color Doppler confirmed a pulsatile feeding vessel within the placental mass.
• The patient delivered spontaneously at 28 weeks gestation; all three fetuses were stillborn.

Implications:

• Histopathological diagnosis confirmed angiomatous chorioangioma.
• Large chorioangiomas represent a grave complication in multiple gestations.
• This case underscores the importance of vigilant monitoring in high-risk pregnancies.