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Updated: Jul 22, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Synthesis and Fluorescence Properties of Imidazopyridine-Linked Coumarins via Tandem C(sp2)-H
Seyyed Emad Hooshmand1, Zahra Amini1, Morteza Shiri2
1Department of Organic Chemistry, Faculty of Chemistry, Alzahra University, Vanak, Tehran, 1993893973, Iran.
Abstract:
A catalyst-, oxidant-free and green synthetic route for direct access to a series of novel imidazopyridine-linked coumarins has been devised through tandem C(sp2)-H functionalization/decarboxylation reaction in ethyl acetate as a sustainable medium. Moreover, the utilities of ensured products in further organic synthesis were conducted by Suzuki-Miyaura and Sonogashira cross-coupling reactions. The fluorescence characteristics of the produced molecules are appropriate, and the synthesized scaffolds could promisingly garner future attention in clinical diagnostics and bioimaging research.
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