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Personalized Integrated Care Promoting Quality of Life for Older People: Protocol for a Multicenter Randomized
Elda Judica1, Peppino Tropea1, Raquel Bouça-Machado2
1Department of Neurorehabilitation Sciences, Casa di Cura Igea, Milan, Italy.
The Personalized Integrated Care Promoting Quality of Life for Older People (PC4L) platform, tested in a large European study, aims to improve quality of life for neurodegenerative disease patients. Results will assess its impact, usability, and feasibility across different care settings.
Area of Science:
- Gerontology and Rehabilitation
- Digital Health and Health Informatics
- Neurodegenerative Disease Management
Background:
- Alzheimer disease (AD) and Parkinson disease (PD) are leading neurodegenerative conditions impacting millions globally.
- The PC4L project developed an integrated, scalable, and interactive care ecosystem adaptable for various chronic diseases and care settings.
- This ecosystem aims to enhance the quality of life for older individuals with neurodegenerative diseases.
Purpose of the Study:
- To iteratively test the PC4L integrated platform and its modules.
- To assess the impact of the PC4L platform on patients' quality of life.
- To evaluate the usability and feasibility of the PC4L platform in diverse care scenarios (home, neurorehabilitation, day care centers) with a large sample size.
Main Methods:
- A prospective, multicenter clinical study involving 558 patients with PD, Parkinsonism, AD, and other dementias (ODs) across 6 pilot centers in 5 European countries.
- Patients were randomized (1:1) to either the intervention group using the PC4L system (wristband for activity monitoring and app) or a control group.
- Clinical evaluations, including the EQ-5D-3L scale for quality of life assessment, were conducted at baseline and study end.
Main Results:
- Recruitment for the study (NCT05538455) is complete, with 558 patients enrolled between September 2022 and February 2023.
- The study, funded by European Commission Horizon 2020, received ethical approvals from all participating centers.
- Expected results will clarify PC4L's impact on quality of life, patient empowerment, medical resource utilization, system usability, and decision-making support.
Conclusions:
- The PC4L project validates a technology-based, integrated care platform for neurodegenerative diseases, proposing an improved coordinated care model.
- Future developments may incorporate caregivers and socio-health professionals to enhance communication and ensure secure data access across Europe.
- The PC4L solution offers a scalable and interactive approach to managing chronic conditions and improving patient outcomes.
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