Related Experiment Video
Updated: Jul 22, 2025

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
Published on: January 31, 2014
Robust PACm: Training Ensemble Models Under Misspecification and Outliers
Abstract:
Standard Bayesian learning is known to have suboptimal generalization capabilities under misspecification and in the presence of outliers. Probably approximately correct (PAC)-Bayes theory demonstrates that the free energy criterion minimized by Bayesian learning is a bound on the generalization error for Gibbs predictors (i.e., for single models drawn at random from the posterior) under the assumption of sampling distributions uncontaminated by outliers. This viewpoint provides a justification for the limitations of Bayesian learning when the model is misspecified, requiring ensembling, and when data are affected by outliers. In recent work, PAC-Bayes bounds-referred to as PACm-were derived to introduce free energy metrics that account for the performance of ensemble predictors, obtaining enhanced performance under misspecification. This work presents a novel robust free energy criterion that combines the generalized logarithm score function with PACm ensemble bounds. The proposed free energy training criterion produces predictive distributions that are able to concurrently counteract the detrimental effects of misspecification-with respect to both likelihood and prior distribution-and outliers.
More Related Videos
04:35Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
Published on: July 3, 2020
12:26Integrating Remote Sensing with Species Distribution Models; Mapping Tamarisk Invasions Using the Software for Assisted Habitat Modeling SAHM
Published on: October 11, 2016
Related Concept Videos
Mechanistic Models: Compartment Models in Individual and Population Analysis
Survival Tree
Building a Survival Tree
Constructing a...
Quantifying and Rejecting Outliers: The Grubbs Test
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Detection of Gross Error: The Q Test
Clearance Models: Noncompartmental Models
The noncompartmental approach capitalizes on extensive sampling data, correlating the volume of distribution to systemic exposure and the administered dosage. This method enables...