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Published on: September 15, 2023
Perioperative Management in Pulmonary Endarterectomy
David P Jenkins1, Guillermo Martinez2, Kiran Salaunkey2
1Department of Cardiothoracic Surgery, Royal Papworth Hospital NHS Foundation Trust, Cambridge Biomedical Campus, Cambridge, United Kingdom.
Pulmonary endarterectomy (PEA) offers improved survival for chronic thromboembolic pulmonary hypertension (PH) patients. Careful perioperative management is crucial for this major surgery, with alternatives available for non-suitable candidates.
Area of Science:
- Cardiothoracic Surgery
- Pulmonary Hypertension Management
Background:
- Chronic thromboembolic pulmonary hypertension (PH) requires specialized treatment.
- Pulmonary endarterectomy (PEA) is the primary surgical option for accessible disease.
Purpose of the Study:
- To detail indications, surgical strategies, and perioperative care for PEA.
- To outline management of residual PH post-PEA.
Main Methods:
- Description of specialized surgical techniques for intra-arterial fibrotic material removal.
- Emphasis on meticulous perioperative management in OR and ICU.
- Discussion of extracorporeal membrane oxygenation for severe complications.
Main Results:
- PEA demonstrates low operative mortality (<5%) in high-volume centers.
- Long-term survival exceeds 70% at 10 years post-successful PEA.
- Significant improvements in morbidity and mortality are documented.
Conclusions:
- PEA is a highly effective treatment for suitable chronic thromboembolic PH patients.
- Management of complications like RV failure and reperfusion edema is critical.
- Balloon pulmonary angioplasty and medical therapy are options for non-surgical candidates or residual PH.
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