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Updated: Jul 22, 2025

Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
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Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice

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Pearls & Oy-sters: MOG-AD Meningoencephalitis With Holocord Gray Matter Predominant Myelitis

Nathan Shmuel Farkas1, Rachel Zolno2, Cristina M Gaudioso2

  • 1From the Department of Neurology (N.S.F.), Thomas Jefferson University, Philadelphia, PA; Department of Neurology (R.Z., C.M.G., S.M.), Washington University in St. Louis School of Medicine; and Mallinckrodt Institute of Radiology (A.Y.M.), St. Louis, MO. nathan.farkas@gmail.com.

Neurology
|July 24, 2023
PubMed

Insights

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) can cause severe brain and spinal cord inflammation. This case highlights a rapid MOGAD presentation in a teen, successfully treated with immunotherapy.

Area of Science:

  • Neurology
  • Immunology
  • Neuroimmunology

Background:

  • Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune condition affecting the central nervous system.
  • MOGAD can manifest with diverse neurological symptoms, including encephalitis and myelitis.

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