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Related Experiment Video

Updated: Jul 22, 2025

Neuroimaging Field Methods Using Functional Near Infrared Spectroscopy NIRS Neuroimaging to Study Global Child Development: Rural Sub-Saharan Africa
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Rural research capacity: a co-created model for research success.

Paige Farris1, Rachel Crist1, Sylvia Miller2

  • 1Community Outreach and Engagement Program, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, 97239, United States of America.

Health Research Policy and Systems
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PubMed
Summary

This study developed a community-engaged strategy to increase clinical trial access in rural areas. The approach successfully facilitated the opening of a cancer early detection trial by improving communication and addressing barriers.

Keywords:
Cancer prevention and controlClinical researchCommunityImplementationRural

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Area of Science:

  • Clinical Research
  • Rural Health
  • Community Engagement

Background:

  • National Institutes of Health (NIH) challenges academia to improve clinical trial enrollment, particularly in underrepresented populations.
  • Rural communities face barriers to clinical trial participation due to limited research infrastructure and staffing.
  • Addressing rural clinical trial access requires considering community receptivity and capacity, not just increasing trial numbers.

Purpose of the Study:

  • To co-create a community-responsive approach for receiving, reviewing, and accepting clinical trials in rural settings.
  • To develop a systematic strategy to increase the number of clinical trials offered in rural communities.
  • To overcome barriers hindering rural residents' participation in clinical trials.

Main Methods:

  • Adapted a 5-step Implementation Mapping approach to develop a systematic strategy.
  • Co-designed a community-responsive process for clinical trial review and acceptance.
  • Pilot-tested the strategy with a cancer early detection trial in a rural community.

Main Results:

  • Successfully implemented a co-designed research review strategy involving community members.
  • Demonstrated strong researcher-community stakeholder communication and negotiation.
  • Led to early identification and resolution of potential barriers, hiring a local coordinator, and timely trial opening.

Conclusions:

  • This work represents the first community-engaged approach for a clinical trial implementation strategy supporting rural stakeholders in reviewing and approving trials.
  • Participating community members and leaders negotiated protocol changes directly with researchers.
  • The strategy supports rural communities in receiving, reviewing, and approving cancer-related clinical trials.