Related Experiment Video
Updated: Jul 21, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
Spectrum of Thyroid Disorders in Patients with Type-2 Diabetes Mellitus
Sandip Ghimire1, Prativa Sangroula1, Indu K C2
1Department of Internal Medicine, Lumbini Medical College and Teaching Hospital, Palpa, Nepal.
Background:
Diabetes mellitus and thyroid disorders are the two most common endocrine disorders and they mutually affect each other. There are very few researches from Nepal that have evaluated the association of type-2 diabetes mellitus and thyroid dysfunction. The main objective of this study was to evaluate the prevalence and spectrum of thyroid dysfunctions among type-2 diabetes mellitus patients.
Methods:
This was cross-sectional study conducted among 204 type-2 diabetes mellitus patients visiting the internal medicine department of a tertiary center located in Kathmandu, Nepal.
Results:
The prevalence of thyroid disorders in patients with type-2 diabetes mellitus was 27.94%. Subclinical hypothyroidism, which occurred in 14.71% of patients, was the most common thyroid disorder. The longer duration of diabetes, more than ten years, was associated with the increased thyroid disorders (p=0.025). The poor glycemic control, HbA1c ≥ 7%, was associated with significantly increased prevalence of thyroid dysfunction in type-2 diabetes mellitus patients (p=0.002). Female patients had higher prevalence of thyroid disorders than males, but this association was not statistically significant.
Conclusions:
The higher prevalence of thyroid disorders among patients with type-2 diabetes mellitus highlights the importance of screening type-2 diabetes mellitus patients for the presence of thyroid disorders.
More Related Videos
Related Concept Videos
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes Mellitus: Type 2 and Gestational
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Diabetes: Symptoms, Diagnosis, and Complications
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

