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You only waste twice: T cells in parasite-induced organ wasting
Felix Clemens Richter1, Andreas Bergthaler1
1Institute of Hygiene and Applied Immunology, Department of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna 1090, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna 1090, Austria.
Abstract:
In this issue of Cell Reports, Redford et al.1 uncouple the role of CD4+ and CD8+ T cells in controlling anorexia and wasting of muscle and adipose tissue during chronic parasitic infections. These results shed light on the impact of adaptive immune cells on organ catabolism.
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