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Related Experiment Video

Updated: Jul 21, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

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[Endoscopic Transsphenoidal Surgery: Basic Technique].

Kosaku Amano1

  • 1Department of Neurosurgery, Tokyo Women's Medical University.

No Shinkei Geka. Neurological Surgery
|July 25, 2023
PubMed
Summary
This summary is machine-generated.

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Transsphenoidal surgery (TSS) has evolved significantly, with microscopy in the 1960s and endoscopy in the 1990s improving safety and efficacy. Modern endoscopic TSS (eTSS) leverages advanced optics for pituitary lesion treatment.

Area of Science:

  • Neurosurgery
  • Otolaryngology
  • Endoscopic Surgery

Context:

  • Transsphenoidal surgery (TSS) is a critical neurosurgical technique for pituitary lesions.
  • Early TSS procedures had high complication and fatality rates, limiting their use.
  • Microscopy in the 1960s and endoscopy in the 1990s revolutionized TSS safety and accessibility.

Purpose:

  • To review the historical development and technical advancements of transsphenoidal surgery.
  • To outline the advantages and disadvantages of modern endoscopic TSS (eTSS).
  • To describe the fundamental techniques employed in endoscopic transsphenoidal surgery.

Summary:

  • Transsphenoidal surgery (TSS) originated in the early 20th century but was hampered by safety concerns.
  • The introduction of microscopy by Hardy et al. in the 1960s established TSS as a safe, standard procedure.

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Last Updated: Jul 21, 2025

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  • Endoscopic advancements, particularly high-definition endoscopes in the 2010s, have further refined endoscopic TSS (eTSS), enhancing its capabilities for pituitary lesion treatment.

    • Impact:

    • Optical instrument advancements have been pivotal in the evolution of TSS.
    • Endoscopic TSS (eTSS) represents a significant improvement over traditional methods.
    • This report provides insights into the benefits, drawbacks, and techniques of eTSS for pituitary surgery.