Risk and protective factors related to having a child with congenital heart diseases (CHD): a case-control study in

Mostafa Amini-Rarani1, Salah Eddin Karimi2, Neda SoleimanvandiAzar3

  • 1Health Management and Economics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

PubMed

Insights

Low socioeconomic status, education, and substance use increase the risk of congenital heart disease (CHD) in children. Folic acid and prenatal care are protective factors, highlighting the need for targeted public health interventions.

Area of Science:

  • Cardiology
  • Public Health
  • Maternal Health

Background:

  • Congenital heart disease (CHD) poses a significant threat, as the heart is the first fully developed organ during early pregnancy.
  • Identifying risk and preventive factors for CHD is crucial for effective management and treatment.

Purpose of the Study:

  • To investigate the multifactorial etiology of CHD by identifying associated risk and protective factors.
  • To provide a scientific basis for CHD prevention and control strategies.

Main Methods:

  • A case-control study involving 600 participants, including 200 mothers of children with CHD.
  • Simple random sampling was employed in 2020, with a matched control group.
  • Data analysis was conducted using SPSS software with a significance level of 0.05.

Main Results:

  • Identified risk factors for CHD include low socioeconomic status, low education, history of abortion, smoking, and alcohol consumption.
  • Protective factors against CHD include folic acid consumption and adequate prenatal care.

Conclusions:

  • Preventive strategies should emphasize maternal education on folic acid and prenatal care, alongside reducing alcohol and tobacco use.
  • Public health interventions should prioritize families with low socioeconomic status and education levels to mitigate CHD risks.
Abstract

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