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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Jul 21, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
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Macular hole Delphi consensus statement (MHOST).

Filippo Confalonieri1,2, Hanna Haave1, Susanne Binder3,4

  • 1Center for Eye Research and Innovative Diagnostics, Department of Ophthalmology, Oslo University Hospital and University of Oslo, Oslo, Norway.

Acta Ophthalmologica
|July 26, 2023
PubMed
Summary
This summary is machine-generated.

This study used the Delphi method to find consensus among surgeons on managing full thickness macular holes (FTMH) and lamellar macular holes (LMH). While some areas reached agreement, significant disagreement persists in surgical decision-making for these common conditions.

Keywords:
DELPHI consensus statementFull thickness macular hole (FTMH)Lamellar Macular Hole (LMH)surgical decision-makingsurgical management

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Retinal Surgery

Background:

  • Macular holes, including Full Thickness Macular Hole (FTMH) and Lamellar Macular Hole (LMH), are common retinal conditions.
  • Standardized surgical management protocols for FTMH and LMH are evolving.
  • Expert consensus can guide clinical decision-making in complex ophthalmic surgeries.

Purpose of the Study:

  • To establish a consensus among vitreoretinal surgeons regarding the surgical management of FTMH and LMH.
  • To identify areas of agreement and disagreement in the diagnosis and treatment of macular holes.
  • To provide a guide for surgical decision-making in FTMH and LMH cases.

Main Methods:

  • A Delphi method-based questionnaire was administered to 37 expert vitreoretinal surgeons.
  • Participants represented 21 European countries.
  • Two rounds of questionnaires were conducted to reach consensus on diagnosis and treatment strategies.

Main Results:

  • Consensus was achieved on 10 out of 36 items in the first round, including intraoperative PVD verification and OCT-based FTMH classification.
  • Areas of agreement included the ineffectiveness of ocriplasmin and specific ILM peeling techniques.
  • Further discussion in round 2 involved 18 items, with final consensus reached on 35% of all questions.
  • Specific consensus points included SF6 gas as preferred tamponade and combined cataract surgery for opaque lenses.

Conclusions:

  • The Delphi study highlights areas of both consensus and significant disagreement in FTMH and LMH surgical management.
  • Variable approaches and ongoing debate exist for these relatively common retinal conditions.
  • The findings offer valuable insights for surgical decision-making and identify areas for future research and standardization.