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Pediatric Pulmonology 2022 year in review: Rare and diffuse lung disease

Andrew T Barber1, Deborah R Liptzin2,3,4, William A Gower5

  • 1Department of Pediatrics, Virginia Commonwealth University, Richmond, Virginia, USA.

Pediatric Pulmonology
|July 26, 2023
PubMed

Insights

Recent advancements in rare pediatric lung diseases offer new insights into diagnosis and treatment for interstitial lung disease, bronchiectasis, and primary ciliary dyskinesia. This review covers 2022 findings on novel disorders, mechanisms, biomarkers, and therapies.

Area of Science:

  • Pediatric Pulmonology
  • Rare lung diseases in children

Background:

  • The field of pediatric rare and diffuse lung diseases is rapidly evolving.
  • Key areas include children's interstitial and diffuse lung disease (chILD), non-cystic fibrosis bronchiectasis, and primary ciliary dyskinesia (PCD).

Purpose of the Study:

  • To review significant advancements in the diagnosis and treatment of rare pediatric lung diseases published in 2022.
  • To contextualize these new findings within the existing body of literature.

Main Methods:

  • Review of papers published in 2022 in Pediatric Pulmonology and other relevant journals.
  • Synthesis of information on newly recognized disorders, disease mechanisms, biomarkers, and treatments.

Main Results:

  • Newly identified rare pediatric lung disorders have been described.
  • Advances in understanding disease mechanisms, natural courses, and potential biomarkers were reported.
  • Novel therapeutic strategies for these conditions were assessed.

Conclusions:

  • The year 2022 brought important progress in the diagnosis and management of rare pediatric lung diseases.
  • Continued research is crucial for further improving outcomes for affected children.

Keywords:
bronchiectasiscongenital abnormalitiesinterstitial lung diseaseprimary ciliary dyskinesia

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