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Published on: July 31, 2019
Curcumin Supplementation and Vascular Health: Is Gut Microbiota Involved?
Samuele Laudani1, Federica Martina Di Domenico1, Nadia Paladino1
1Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Abstract:
Curcumin is a polyphenol compound widely investigated for its potential health benefits. Clinical evidence from randomized controlled trials shows substantial positive effects in healthy individuals but contrasting results for patients with cardio-metabolic disorders. There is growing evidence that the gut microbiota may play a role in curcumin transformation and absorption of more bioactive compounds, suggesting that the baseline health status (or other unmeasured variables) may explain the observed variability of the results.
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