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Immunohistochemistry Should Be Regulated as an Assay

Barbarajean Magnani1, Clive R Taylor2

  • 1From the Department of Anatomic and Clinical Pathology, Tufts University School of Medicine, Boston, Massachusetts (Magnani).

Archives of Pathology & Laboratory Medicine
|July 26, 2023
PubMed
Summary

No abstract available in PubMed .

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Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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