Related Experiment Video
Updated: Aug 19, 2026

Rapid Analysis of Chromosome Aberrations in Mouse B Lymphocytes by PNA-FISH
Published on: August 19, 2014
[Chromosome aberrations and reproductive death of mammalian cells. Quantitative relations between these effects]
Abstract:
The data reported in the literature concerning the relationship between the yield of chromosome aberrations and the number of cells without aberrations, on the one hand, and the survival rate of mammalian cells, on the other, with a reference to different types of radiation are reviewed in this article. It is shown that the number of chromosome aberrations per one lethal damage, as to the results obtained by different authors, ranges from 0.5 to 1.5, this discrepancy is mainly due to different methods applied by different authors, and at least one chromosome aberration corresponds to a lethal damage caused by irradiation in the G1 phase.
More Related Videos
10:14Detection of Inter-chromosomal Stable Aberrations by Multiple Fluorescence In Situ Hybridization (mFISH) and Spectral Karyotyping (SKY) in Irradiated Mice
Published on: January 11, 2017
09:24Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination
Published on: July 18, 2025
Related Concept Videos
Meiosis I
Nondisjunction
Fixing Double-strand Breaks
Meiosis I
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Meiosis vs. Mitosis
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Nondisjunction