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Computerized Cognitive Training and 24-Month Mortality in Heart Failure.
The Journal of Cardiovascular Nursing
|July 26, 2023
Summary
Computerized cognitive training did not reduce mortality in heart failure patients over 24 months. However, older age, poor cognition, and depression predicted mortality in this population.
Area of Science:
- Cardiology
- Neurology
- Gerontology
Background:
- Cognitive dysfunction is a significant predictor of mortality in heart failure (HF) patients.
- Computerized cognitive training (CCT) shows potential for cognitive improvement, but its impact on mortality in HF remains uncertain.
Purpose of the Study:
- To assess the long-term efficacy of CCT in reducing 24-month mortality among HF patients.
- To identify predictors of 24-month mortality, including age, HF severity, cognitive function, depressive symptoms, and quality of life.
Main Methods:
- A prospective longitudinal study involving 142 HF patients from a 3-arm randomized controlled trial.
- Data collected over 24 months, analyzed using logistic regression.
Main Results:
- A total of 16 deaths occurred within 24 months (CCT group: 8.3%; control groups: 12.8%).
- CCT did not significantly predict 24-month mortality (OR, 0.65).
- Predictors of mortality included older age (OR, 1.08), worse global cognition (OR, 0.73), impaired memory (OR, 0.81), and higher depressive symptoms (OR, 1.10) at baseline.
Conclusions:
- There is a need for effective interventions to enhance cognitive function (global cognition, memory) and manage depressive symptoms to reduce mortality in HF patients.
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