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Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
Stimulus control for insomnia: A systematic review and meta-analysis
Markus Jansson-Fröjmark1, Lisa Nordenstam1, Sven Alfonsson1
1Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm Health Care Services, Stockholm, Sweden.
Stimulus control (SC) effectively improves sleep onset latency and total sleep time for insomnia compared to passive treatments. While SC shows comparable results to active treatments, further research is needed for definitive conclusions.
Area of Science:
- Behavioral Science
- Sleep Medicine
- Psychology
Background:
- Stimulus control (SC) is a recognized insomnia treatment, yet lacks comprehensive evaluation using modern meta-analytic techniques.
- This study systematically reviews and meta-analyzes randomized controlled and experimental trials on SC efficacy for insomnia.
Approach:
- Conducted a systematic literature search across six databases for eligible studies.
- Included 11 studies (adults) comparing SC to passive/active comparators, assessing sleep diary outcomes.
- Utilized a random effects model to calculate standardized mean differences (Hedge's g) for awakenings, sleep onset latency, and total sleep time.
Key Points:
- SC demonstrated small to large improvements in sleep onset latency and total sleep time versus passive comparators (g = 0.38–0.85).
- Improvements with SC were negligible compared to active comparators (g = 0.06–0.30).
- Methodological limitations were noted in the included trials.
Conclusions:
- Stimulus control appears efficacious for insomnia, particularly when compared to passive interventions.
- SC shows similar efficacy to active comparator treatments for insomnia.
- More rigorous research is recommended to solidify these findings and guide clinical practice.
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