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HHV-6 Myocarditis Progressing to Ventricular Standstill Requiring Cardiac Transplant

Stephanie Golob1, Haider Nazeer1, Bernard Kadosh1

  • 1Division of Cardiology, NYU Langone Medical Center, New York, New York, USA.

JACC. Case Reports
|July 27, 2023
PubMed

Insights

Human herpesvirus-6 (HHV-6) causes severe myocarditis. This case highlights fulminant HHV-6 myocarditis in a woman requiring a heart transplant, emphasizing HHV-6 as a critical cardiac pathogen.

Area of Science:

  • Cardiology
  • Virology
  • Immunology

Background:

  • Human herpesvirus-6 (HHV-6) is an emerging cause of myocarditis.
  • Myocarditis is inflammation of the heart muscle, potentially leading to severe cardiac dysfunction.

Observation:

  • A 46-year-old woman presented with fulminant myocarditis.
  • Diagnosis revealed Human herpesvirus-6 (HHV-6) as the causative agent.

Findings:

  • The patient experienced severe cardiac compromise due to HHV-6 infection.
  • Fulminant myocarditis necessitated advanced medical intervention.

Implications:

  • HHV-6 should be considered in cases of severe, unexplained myocarditis.
  • Early diagnosis and management of HHV-6 myocarditis are crucial for patient outcomes.
  • This case underscores the need for heart transplantation in severe HHV-6-induced myocarditis.

Keywords:
acute heart failurecardiac transplantcardiomyopathy

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