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Diffuse large B-cell lymphoma in large intestine presenting as multiple polypoid lesions
Summary
Diffuse large B-cell lymphoma (DLBCL) typically presents as a single large ulcerated mass. This case highlights an unusual presentation of DLBCL with multiple polypoid lesions in the large intestine.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
- Colonic involvement by DLBCL can manifest in various ways, often presenting as a solitary ulcerated mass during endoscopic examination.
Observation:
- A 54-year-old male patient presented with multiple polypoid lesions in the large intestine.
- These lesions represented an atypical endoscopic morphology for DLBCL.
Findings:
- The patient was diagnosed with diffuse large B-cell lymphoma (DLBCL).
- The morphological presentation of multiple polypoid lesions is an uncommon manifestation of colonic DLBCL.
Implications:
- This case underscores the importance of considering DLBCL in the differential diagnosis of polypoid colonic lesions.
- Recognizing uncommon morphological variants of DLBCL is crucial for timely diagnosis and appropriate treatment planning.
- Further research into the diverse endoscopic presentations of gastrointestinal lymphomas may improve diagnostic accuracy.
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