Pediatric oncohematological exercise program in hospital: clinical trial study protocol

Cintia Freire Carniel1, Beatriz M Rosin1, Bruna Cunha de Souza1

  • 1Laboratório de Delineamento de Estudos e Escrita Científica, Centro Universitário FMABC, Santo André, São Paulo, 09060-590, Brazil.

Insights

Therapeutic exercises may improve functional capacity, strength, and quality of life in children with leukemia. This study compares exercise protocols to standard physiotherapy during hospitalization.

Area of Science:

  • Pediatric Oncology
  • Hematology
  • Rehabilitation Medicine

Background:

  • Leukemia is the most common childhood cancer, significantly impairing functional capacity.
  • Therapeutic exercises show promise in improving functional outcomes in various pediatric conditions.

Purpose of the Study:

  • To evaluate the impact of a therapeutic exercise protocol on functional capacity, muscle strength, fatigue, and quality of life in hospitalized children with leukemia.
  • To compare the effects of a specific therapeutic exercise protocol against conventional respiratory physiotherapy.

Main Methods:

  • A randomized controlled trial will be conducted with pediatric leukemia patients.
  • Participants will be allocated to either a therapeutic exercise group or a conventional respiratory physiotherapy group.
  • Functional capacity, muscle strength, fatigue, and quality of life will be assessed.

Main Results:

  • This section is to be filled upon study completion.

Conclusions:

  • This section is to be filled upon study completion.

Related Concept Videos

Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
3.0K
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
6.9K
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
360
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.3K