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Bicuspid aortic valve and its ascending aortopathy

Emma C Dunne1, Ronald V Lacro2,3, Jonathan N Flyer1,4

  • 1The Robert Larner, M.D. College of Medicine at The University of Vermont, Burlington, Vermont.

Current Opinion in Pediatrics
|July 27, 2023
PubMed

Insights

Pediatric bicuspid aortic valve (BAV) research highlights familial screening, safe exercise, and medical management to prevent aortic dilation and improve long-term outcomes for children with BAV.

Area of Science:

  • Cardiovascular Medicine
  • Pediatric Cardiology
  • Genetics

Background:

  • Bicuspid aortic valve (BAV) is a common congenital heart defect.
  • BAV is associated with progressive aortic dilation, termed bicuspid aortopathy.
  • Bicuspid aortopathy increases risks for aortic aneurysm, dissection, and adult surgery.

Conclusions:

  • Pediatric bicuspid aortopathy requires further investigation and preventive strategies.
  • Recent literature supports familial screening, exercise, medical prophylaxis, and registry-based evaluation.
  • Continued scientific inquiry is crucial for improving long-term cardiovascular outcomes in pediatric BAV patients.
Abstract

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