Olfaction preservation in olfactory groove meningiomas: a systematic review

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Nicholas G Candy1, Dominik Hinder2, Alistair K Jukes3

  • 1Department of Surgery Otolaryngology, Head and Neck Surgery, The University of Adelaide, Basil Hetzel Institute for Translational Research, Woodville South, Adelaide, Australia. Nicholas.g.candy@gmail.com.

Neurosurgical Review
|July 27, 2023
PubMed

Insights

Olfactory groove meningiomas (OGM) surgery can preserve smell function using various approaches. Further research is needed to optimize OGM treatment pathways with objective olfactory and quality-of-life assessments.

Area of Science:

  • Neurosurgery
  • Skull Base Surgery
  • Oncology

Background:

  • Olfactory groove meningiomas (OGM) constitute 8-13% of intracranial meningiomas.
  • Surgical approaches prioritize frontal lobe decompression, gross total resection, and vision preservation.
  • Olfactory preservation is increasingly recognized as a critical quality-of-life outcome.

Approach:

  • A systematic review and meta-analysis was conducted following PRISMA guidelines.
  • Databases searched included Medline, Scopus, Embase, Web of Science, and Cochrane Library.
  • Six articles reporting quantitative olfactory outcomes using smell identification tests were included.

Key Points:

  • Objective olfactory preservation is achievable through diverse surgical techniques for OGM.
  • Quantitative assessment of olfaction using standardized tests (e.g., Sniffin' Sticks) is crucial.
  • The included studies focused on surgical outcomes and olfactory function.

Conclusions:

  • Current surgical strategies can achieve objective olfaction preservation in OGM patients.
  • Further research incorporating objective olfactory function and quality-of-life measures is essential.
  • Optimizing treatment pathways for OGM necessitates comprehensive outcome assessments.
Keywords:
Endoscopic surgeryMeningiomaNeurosurgeryOlfaction

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