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A novel method of measuring proptosis with computed tomography
Rou Sun1,2, Ziqing Yin1,2, Lunhao Li1,2
1Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Acta Radiologica (Stockholm, Sweden : 1987)
|July 28, 2023
Summary
A new semi-automatic method using MedrawHDC software reliably measures proptosis on CT scans. This accessible and reproducible technique offers clinical value for proptosis assessment.
Area of Science:
- Ophthalmology
- Radiology
- Medical Imaging
Background:
- Computed tomography (CT) is a standard for measuring proptosis, minimizing interference.
- Existing software aids in clinical proptosis measurement.
Purpose of the Study:
- To develop and validate a novel semi-automatic CT-based method for proptosis measurement.
- To assess the accuracy and reproducibility of this new method.
Main Methods:
- A new software, MedrawHDC, was developed for semi-automatic proptosis measurement on CT.
- The MedrawHDC method was compared against the classic radiological (CR) method and Hertel's exophthalmometer (HE).
- Reproducibility was assessed with multiple observers using the MedrawHDC method.
Main Results:
- The MedrawHDC method demonstrated high consistency with the CR method across normal, Graves ophthalmopathy (GO), and orbital fracture (OF) groups (ICC > 0.979).
- Measurements by MedrawHDC and CR methods correlated well with the HE method in the GO group (ICC ≈ 0.697).
- Inter-observer reproducibility for the MedrawHDC method was excellent (ICC = 0.995).
Conclusions:
- The MedrawHDC method is a reliable, accessible, and reproducible tool for proptosis assessment.
- This new technique holds significant clinical value for the scientific evaluation of proptosis.
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