Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Scanning Electron Microscopy Identification of Microscopic Onyx Fragments in Blood Aspirated from a Distal Access Catheter after Arteriovenous Malformation Embolization: A Case Report.

Journal of neuroendovascular therapy·2026
Same author

Incidence and Outcomes of Flow Diverter Braid Deformation following Treatment with Non-DFT Wire Devices.

Neurologia medico-chirurgica·2026
Same author

Management of unruptured intracranial aneurysms in atrial fibrillation: Role of ablation in anticoagulation cessation.

Journal of cardiology cases·2026
Same author

Intentional staged angioplasty with superficial temporal artery-superior cerebellar artery "safety bypass" for symptomatic severe vertebral artery stenosis: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Lipoxins Regulate Intercalated Disk-Associated Signaling and Immune Remodeling in Dilated Cardiomyopathy.

bioRxiv : the preprint server for biology·2026
Same author

Comparison of the Safety and Efficacy between Endovascular Coiling and Surgical Clipping of Posterior Communicating Artery Aneurysms: A 10-year Retrospective Analysis of 851 Aneurysms.

Neurologia medico-chirurgica·2026

Related Experiment Video

Updated: Jul 21, 2025

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

9.7K

Simulation Model of Arteriovenous Malformation Embolization Using Onyx.

Fuga Ayabe1,2, Kazutaka Sumita1, Shoko Fujii1

  • 1Department of Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.

Journal of Neuroendovascular Therapy
|July 28, 2023
PubMed
Summary

This study developed a 3D-printed arteriovenous malformation (AVM) model for simulating Onyx embolization. The model accurately replicates clinical AVM embolization, aiding in training and improving technical skills for this complex procedure.

Keywords:
Onyxarteriovenous malformationsimulation model

More Related Videos

A Patient-Derived Xenograft Model for Venous Malformation
06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.4K
The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
08:53

The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering

Published on: November 2, 2016

12.6K

Related Experiment Videos

Last Updated: Jul 21, 2025

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

9.7K
A Patient-Derived Xenograft Model for Venous Malformation
06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.4K
The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
08:53

The Arteriovenous AV Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering

Published on: November 2, 2016

12.6K

Area of Science:

  • Biomedical Engineering
  • Interventional Radiology
  • Medical Simulation

Background:

  • Arteriovenous malformations (AVMs) require complex endovascular embolization.
  • Onyx is an effective embolic agent but demands significant operator skill.
  • Technical challenges in Onyx infusion necessitate improved training methods.

Purpose of the Study:

  • To develop a realistic simulation model for Onyx embolization of AVMs.
  • To address the technical difficulties associated with Onyx infusion in AVM treatment.
  • To provide a training tool for interventional radiologists.

Main Methods:

  • A 3D-printed acrylonitrile-butadiene-styrene (ABS) resin model of an AVM was created from 3D DSA images.
  • A hollow elastic model was fabricated using silicone over the ABS resin, which was subsequently eluted.
  • The AVM model was integrated into a human vascular model for comprehensive simulation.

Main Results:

  • Simulated angiography and Onyx embolization demonstrated comparable angiographic features to clinical cases.
  • The model accurately reproduced the flow dynamics of contrast media and Onyx.
  • The 'plug and push' technique, crucial for Onyx embolization, was successfully performed on the model.

Conclusions:

  • A 3D-printed AVM model effectively simulates Onyx embolization procedures.
  • This simulation model can enhance training and skill acquisition for AVM embolization.
  • The developed model offers a valuable tool for mastering complex endovascular techniques.