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Updated: Jul 21, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Mechanical Thrombectomy for Acute Ischemic Stroke Complicated by Bacterial Meningitis and Infective Endocarditis
Masaaki Kubota1,2, Eiichi Kobayashi1,2, Yoichi Yoshida1,2
1Comprehensive Stroke Center, Chiba University Hospital, Chiba, Chiba, Japan.
Objective:
We report a case of cerebral embolism from a bacterial embolus due to infective endocarditis (IE) during treatment of bacterial meningitis.
Case Presentation:
During treatment of bacterial meningitis, an 82-year-old woman developed left middle cerebral artery embolism. Mechanical thrombectomy was performed, and the yellowish-white emboli were retrieved. From the culture and pathological findings of the embolus, the same bacteria as the meningitis, Streptococcus gordonii, was identified and was considered to originate from IE. She was treated by postoperative antibiotics, but was transferred to the rehabilitation hospital on the 37th postoperative day due to slight right hemiparesis.
Conclusion:
We should always consider bacterial embolism in acute ischemic stroke combined with bacterial meningitis.
Insights
Infective endocarditis (IE) can cause bacterial meningitis and cerebral embolism. This case highlights the importance of considering IE in patients with acute ischemic stroke and meningitis.
Area of Science:
- Neurology
- Infectious Diseases
- Cardiology
Background:
- Bacterial meningitis can lead to serious complications, including stroke.
- Infective endocarditis (IE) is a serious infection of the heart valves that can cause embolic events.
Observation:
- An 82-year-old woman with bacterial meningitis developed a left middle cerebral artery embolism during treatment.
- Mechanical thrombectomy successfully retrieved yellowish-white emboli.
- Culture and pathological findings identified *Streptococcus gordonii* in the emboli, matching the meningitis pathogen and suggesting IE as the source.
Findings:
- The retrieved emboli were confirmed to be bacterial, originating from infective endocarditis.
- The patient experienced slight right hemiparesis post-procedure.
Implications:
- This case underscores the critical need to consider bacterial embolism from IE in patients presenting with acute ischemic stroke concurrent with bacterial meningitis.
- Early recognition and management of IE are crucial to prevent severe neurological sequelae.
Related Concept Videos
Endocarditis III: Medical Management
Venous Thrombosis III: Interprofessional Care
Endocarditis I: Introduction
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Endocarditis IV: Nursing Management
Mitral Stenosis III: Medical Management

