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Updated: Jul 21, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Results of an International Questionnaire Investigating Changes in Acute Stroke Management between Before and During
Kyohei Fujita1, Shoko Fujii1, Hiroto Yamaoka1
1Department of Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Insights
Stroke management largely unchanged during COVID-19, but infection rates and patient mortality increased. This study examined changes in acute stroke care during the pandemic.
Area of Science:
- Neurology
- Infectious Diseases
- Public Health
Background:
- The coronavirus disease 2019 (COVID-19) pandemic significantly impacted healthcare systems globally.
- Acute stroke management requires timely and specialized interventions, potentially complicated by infectious disease outbreaks.
Purpose of the Study:
- To investigate changes in acute stroke patient management before and during the COVID-19 pandemic.
- To assess the impact of the pandemic on stroke care protocols and outcomes across different countries.
Main Methods:
- A questionnaire survey was distributed to 23 stroke centers in 20 countries.
- Data collected compared stroke management practices in 2019 (pre-pandemic) versus 2020 (during the pandemic).
- Responses were analyzed from 14 stroke centers in 14 countries.
Main Results:
- Most stroke centers (85%) maintained unchanged imaging and endovascular thrombectomy (ET) indications post-COVID-19 precautions.
- However, 50% of centers reported a 10-70% decrease in ET procedures.
- Confirmed COVID-19 transmission occurred in 29% of centers, with 25% experiencing hospital-acquired infections; 50% of ET patients died, often from COVID-19 complications.
Conclusions:
- Stroke management strategies remained largely consistent, with adaptations focused on COVID-19 precautions.
- Significant increases in hospital-acquired infections and patient morbidity/mortality were observed, linked to COVID-19 systemic complications.
- The pandemic posed challenges to stroke care, affecting treatment volume and patient outcomes despite successful interventions.
Objective:
The present study investigated changes in the management of acute stroke patients between before and during the coronavirus disease 2019 (COVID-19) pandemic in several countries using a questionnaire.
Methods:
A questionnaire survey was conducted at 23 stroke centers in 20 countries to examine how stroke management systems have changed from 2019 (before the COVID-19 pandemic) to 2020 (during the COVID-19 pandemic).
Results:
Questionnaire responses were obtained from 14 stroke centers (61%) in 14 countries. Among the surveyed stroke centers, 36% utilized full personal protective equipment (PPE) including N95 masks in all cases. After the proper application of infection precautions and screening for COVID-19, the initial imaging modality and indications for endovascular thrombectomy (ET) for ischemic stroke remained unchanged in more than 85% of the surveyed stroke centers. The transmission of COVID-19 from stroke patients to doctors or nurses was confirmed in 29% of the surveyed stroke centers, and hospital-acquired infection from patients to other patients occurred in 25%. The number of cases undergoing ET decreased by 10-70% in 50% of stroke centers during the COVID-19 pandemic. Despite successful recanalization, 50% of patients who underwent ET died, and death was mainly attributed to COVID-19-related systemic complications.
Conclusion:
No significant differences were observed in stroke management or treatment strategies between before and during the COVID-19 pandemic in most stroke centers, except for COVID-19 precautions. However, the higher proportion of hospital-acquired infections and increased morbidity rate among patients despite successful recanalization due to COVID-19-related systemic complications are important findings.
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