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Updated: Jul 21, 2025

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Deciphering Phage-Host Specificity Based on the Association of Phage Depolymerases and Bacterial Surface Glycan with

Yiyan Yang1, Keith Dufault-Thompson1, Wei Yan1

  • 1National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.

Biorxiv : the Preprint Server for Biology
|July 28, 2023
PubMed
Summary

We developed SpikeHunter, a new method using AI to identify phage tailspike proteins, crucial for determining bacterial host specificity. This tool helps discover new phage therapies by linking proteins to bacterial serotypes.

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