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Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series
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Flagellar motor remodeling during swarming requires FliL
Jonathan D Partridge1, Yann Dufour2, YuneSahng Hwang1
1Department of Molecular Biosciences and the LaMontagne Center for Infectious Diseases The University of Texas at Austin, Austin, Texas, 78712, USA.
Biorxiv : the Preprint Server for Biology
|July 28, 2023
Summary
FliL protein remodels bacterial flagellar motors for enhanced swarming motility in diverse species like E. coli. This protein is crucial for increased cell speed and suppressed tumbling during surface movement.
Area of Science:
- Microbiology
- Bacterial Motility
- Molecular Biology
Background:
- FliL is a component of bacterial flagella, essential for motility.
- Its role in swarming, a surface-based movement, is conditional and linked to motor function.
- Swarming requires increased flagellar torque and physiological adaptations.
Conclusions:
- FliL plays a conserved role in remodeling flagellar motors for efficient swarming motility across diverse bacterial species.
- The interaction with FliF's RBM-3 domain is critical for FliL's function in motor regulation.
- Understanding FliL's function provides insights into bacterial adaptation to surface environments.
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