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FastKnock: An efficient next-generation approach to identify all knockout strategies for strain optimization.

Leila Hassani1, Mohammad R Moosavi1, Payam Setoodeh1

  • 1Shiraz University.

Research Square
|July 28, 2023
PubMed
Summary

FastKnock is a new computational algorithm that identifies gene knockout strategies for metabolic engineering. It significantly speeds up the process of finding optimal production strains for biochemicals.

Keywords:
biochemical overproductiongenome-scale metabolic modelgrowth-coupled biosynthesismathematical optimizationreaction clusteringreaction knockout strategysearch space reduction

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