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Updated: Jul 21, 2025

Polydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients
Published on: February 23, 2017
Alexandra R Spitzer1, Shelby B Hutchens1,2
1Department of Materials Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Mechanical deformation significantly impacts water transport in soft solids like polydimethylsiloxane (PDMS). This study reveals that PDMS permeability to water decreases dramatically with increased stretching, affecting mechano-permselectivity.
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