Related Experiment Video
Updated: Jul 21, 2025
12:17
Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
11.4K
Conventional vs. Sutureless Aortic Valve Bioprosthesis: Is Faster Better?
Ali Aljalloud1,2, Ajay Moza1, Jessica Paola Arias1
1Department of Thoracic and Cardiovascular Surgery, RWTH University Hospital Aachen, 52074 Aachen, Germany.
Journal of Cardiovascular Development and Disease
|July 28, 2023
Summary
Sutureless aortic valve replacement (su-AVR) with the Perceval prosthesis showed no superiority over conventional aortic valve replacement (AVR) with the Labcor Dokimos Plus bioprosthesis. Clinical outcomes were equivalent, suggesting case-by-case suitability, especially for elderly patients.
Area of Science:
- Cardiovascular Surgery
- Biomaterials in Medicine
- Prosthetic Devices
Background:
- Sutureless aortic valve replacement (su-AVR) offers potential advantages like reduced procedure time.
- However, its superiority over conventional aortic valve replacement (AVR) remains debated.
- This study compares early outcomes of sutureless Perceval vs. conventional Labcor Dokimos Plus bioprostheses.
Purpose of the Study:
- To compare the early clinical outcomes and performance of sutureless Perceval AVR versus conventional Labcor Dokimos Plus AVR.
- To evaluate differences in mortality, hospital stay, pacemaker implantation, and echocardiographic parameters.
Main Methods:
- A comparative study of 141 Perceval and 138 Labcor Dokimos Plus bioprostheses implanted between 2014-2019.
- Matched cohort analysis of 201 patients based on STS mortality risk and LDH levels.
- Primary endpoints: 30-day mortality, hospital stay, pacemaker implantation. Secondary endpoints: echocardiographic data, adverse events, prosthesis failure.
Main Results:
- Shorter bypass and cross-clamp times were observed with Perceval, but hospital stays were longer.
- No significant difference in 30-day mortality between the groups.
- Perceval group showed higher transvalvular gradients and lower effective orifice area, with higher post-operative LDH levels.
Conclusions:
- Perceval bioprosthesis demonstrated equivalent clinical outcomes to the Dokimos bioprosthesis.
- Sutureless AVR is not definitively superior to conventional AVR in this comparison.
- Perceval suitability should be individualized, particularly for elderly patients with comorbidities.
