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Updated: Jul 21, 2025
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Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
259
A cost-effective transperineal prostate biopsy method utilizes the original transrectal setting
Richard C Wu1,2,3,4, Mu-Chaio Tung1, Chun-Hsien Wu1,3,4
1Department of Urology, E-Da Hospital, Kaohsiung, Taiwan.
International Urology and Nephrology
|July 28, 2023
Summary
Transperineal prostate biopsy (TPB) is a safe and effective alternative to transrectal prostate biopsy (TRB) for prostate cancer diagnosis. This novel TPB technique demonstrated similar cancer detection rates and fewer complications, making it a cost-effective option for urology practices.
Area of Science:
- Urology
- Oncology
- Medical Devices
Background:
- Transperineal prostate biopsy (TPB) presents an alternative to transrectal prostate biopsy (TRB) for diagnosing prostate cancer.
- Potential increased costs associated with TPB may hinder its adoption in urology practices.
Purpose of the Study:
- To report the initial experience with a novel transperineal prostate biopsy (TPB) technique.
- To evaluate the safety, feasibility, and cost-effectiveness of TPB compared to TRB.
Main Methods:
- A retrospective review of 118 prostate biopsies conducted between January and October 2021.
- Comparison of cancer detection rates (CDR) and complication rates between TPB and TRB groups.
- Both techniques utilized a convex-convex array ultrasound probe under local anesthesia with or without sedation.
Main Results:
- TPB and TRB groups showed similar cancer detection rates (46.8% vs. 44.8%) when excluding MRI-targeted biopsy cores.
- TPB group experienced significantly lower general complication rates (27.7% vs. 46.6%).
- No infectious complications were observed in the TPB group, compared to five in the TRB group.
Conclusions:
- Transperineal prostate biopsy (TPB) using a convex-convex ultrasound probe and double free-hand technique is safe, feasible, and cost-effective.
- TPB demonstrates equivalent cancer detection rates to TRB.
- This technique may reduce infectious hospitalizations and minimize the capital investment for adopting TPB.
