Relationship Between Pericallosal Lipoma and Neuropsychiatric Symptoms: A Case Report

Area of Science:

• Neuroscience
• Developmental Biology
• Radiology

Background:

• Intracranial lipomas are rare, congenital fat-containing tumors arising from abnormal embryonic meningeal differentiation.
• Pericallosal lipomas, a subtype associated with the corpus callosum, are the most common intracranial lipomas.
• These lesions often present with corpus callosum dysgenesis, leading to diverse clinical manifestations.

Observation:

• A 15-year-old male patient presented with a history of developmental delay and psychiatric symptoms.
• Magnetic resonance imaging (MRI) incidentally revealed a pericallosal lipoma.
• The incidental finding prompted further clinical evaluation and correlation.

Findings:

• The case illustrates a pericallosal lipoma associated with developmental delay and psychiatric symptoms.
• The imaging findings confirmed the presence of a fat-containing lesion near the corpus callosum.
• Correlation of imaging with clinical presentation was crucial for diagnosis.

Implications:

• This case underscores the importance of considering pericallosal lipomas in patients with unexplained developmental and psychiatric issues.
• Incidental MRI findings of pericallosal lipomas necessitate thorough clinical assessment.
• Understanding the spectrum of clinical presentations associated with corpus callosum dysgenesis is vital for patient management.