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Updated: Jul 21, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
MetaFed: Federated Learning Among Federations With Cyclic Knowledge Distillation for Personalized Healthcare
Abstract:
Federated learning (FL) has attracted increasing attention to building models without accessing raw user data, especially in healthcare. In real applications, different federations can seldom work together due to possible reasons such as data heterogeneity and distrust/inexistence of the central server. In this article, we propose a novel framework called MetaFed to facilitate trustworthy FL between different federations. MetaFed obtains a personalized model for each federation without a central server via the proposed cyclic knowledge distillation. Specifically, MetaFed treats each federation as a meta distribution and aggregates knowledge of each federation in a cyclic manner. The training is split into two parts: common knowledge accumulation and personalization. Comprehensive experiments on seven benchmarks demonstrate that MetaFed without a server achieves better accuracy compared with state-of-the-art methods [e.g., 10%+ accuracy improvement compared with the baseline for physical activity monitoring dataset (PAMAP2)] with fewer communication costs. More importantly, MetaFed shows remarkable performance in real-healthcare-related applications.
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