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Photobiomodulation Therapy in Carpal Tunnel Release: A Randomized Controlled Trial
Jia Peng Chuah1, Saw Sian Khoo1, Tze Yang Chung2
1National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL), Department of Orthopaedic Surgery, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Photobiomodulation, Photomedicine, and Laser Surgery
|July 28, 2023
Summary
Photobiomodulation therapy (PBMT) significantly improved recovery after carpal tunnel release (CTR) surgery. Patients receiving PBMT experienced reduced pain and better functional outcomes compared to those without PBMT.
Area of Science:
- Orthopedics
- Regenerative Medicine
- Biomedical Engineering
Background:
- Carpal tunnel release (CTR) is a common surgical treatment for carpal tunnel syndrome.
- Postoperative recovery can be prolonged and incomplete, necessitating improved therapeutic strategies.
- Photobiomodulation therapy (PBMT) is known to promote nerve healing and reduce inflammation.
Purpose of the Study:
- To evaluate the efficacy of postoperative photobiomodulation therapy (PBMT) in enhancing recovery following carpal tunnel release (CTR).
- To compare clinical outcomes in patients undergoing CTR with and without adjunctive PBMT.
Main Methods:
- A randomized controlled study involving 56 patients who underwent open CTR.
- Patients were divided into two groups: one receiving PBMT (10 sessions over 3 weeks) and a control group.
- PBMT utilized an 808 nm wavelength, 50 mW device delivering 9 J per session to the incision scar.
- Clinical outcomes, including functional status, pain, pinch strength, and 2-point discrimination, were assessed at 1, 3, and 6 months postoperatively.
Main Results:
- The PBMT group showed significant improvements in the Boston Carpal Tunnel Questionnaire Functional Status Scale and morning pain at 1 month.
- Enhanced pinch strength (tip, lateral, tripod) and 2-point discrimination (thumb, index finger) were observed in the PBMT group at various postoperative intervals.
- No adverse side effects were reported with the use of PBMT.
Conclusions:
- Postoperative PBMT is associated with improved functional recovery, reduced pain, and enhanced sensory and motor function after CTR.
- PBMT demonstrates potential as a valuable adjunct therapy to optimize outcomes for patients undergoing carpal tunnel release.
- Further research may explore long-term benefits and optimal PBMT protocols for post-CTR care.

