[Optimal anion composition of the perfusate for preservation of the liver]

The search for optimal concentrations of fumarate, malate, acetate, lactate, asparginate and sulphate in the perfusate was performed in 187 experiments with 2 h perfusion of the isolated rabbit liver at different temperature regimens of conservation. Nonlinear relation between the optimal anion composition of the perfusate and temperature of the liver conservation was found. The critical point in changes of the optimal concentrations of anions in the perfusate was shown to be 10-12 degrees C.