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How to reduce medications for people with multiple long term conditions
Helen Saul1, Samantha Cassidy1, Brendan Deeney1
1NIHR Evidence, Twickenham, UK.
BMJ (Clinical Research Ed.)
|July 28, 2023
Summary
Deprescribing medications for older adults with multiple health conditions and polypharmacy can be done safely. The TAILOR evidence synthesis provides guidance for deprescribing in this population.
Area of Science:
- Geriatric Medicine
- Clinical Pharmacy
- Evidence Synthesis
Background:
- Older adults often have multiple chronic conditions (multimorbidity).
- Polypharmacy, the regular use of multiple medications, is common in this group.
- Managing multiple medications in older adults with multimorbidity presents significant challenges.
Purpose of the Study:
- To synthesize evidence on deprescribing medications in older people with multimorbidity and polypharmacy.
- To provide guidance on the safe and effective deprescribing of medications.
- To support healthcare professionals in optimizing medication regimens for this population.
Main Methods:
- Systematic literature review and evidence synthesis.
- Analysis of data from relevant clinical trials and observational studies.
- Development of evidence-based recommendations for deprescribing.
Main Results:
- Identified strategies and interventions for safe medication reduction.
- Highlighted potential benefits of deprescribing, including reduced adverse events.
- Provided a framework for assessing medication appropriateness in older adults with multimorbidity.
Conclusions:
- Deprescribing is feasible and beneficial for older adults with multimorbidity and polypharmacy.
- A structured, evidence-based approach is crucial for safe deprescribing.
- Implementation of deprescribing strategies can improve patient outcomes and reduce medication burden.
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