Eyes and the heart: what a clinician should know

Jing Yong Ng1, Essa Zarook1, Luke Nicholson2,3

  • 1Medical Education Department, Queen Mary University of London, Barts and the London School of Medicine and Dentistry, London, UK.

PubMed

Insights

Ocular signs can indicate underlying cardiovascular disease. This review highlights the connection between eye conditions and systemic cardiovascular health, aiding diagnosis and management.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Systemic Diseases

Background:

  • The eye can manifest signs of primary ocular or systemic diseases, including cardiovascular conditions.
  • Systemic diseases like hypertension, diabetes, and autoimmune disorders have distinct ocular presentations.
  • Neuromuscular and connective tissue diseases also exhibit characteristic ocular and cardiac findings.

Purpose of the Study:

  • To review the intricate relationship between ocular and cardiovascular systems.
  • To emphasize the diagnostic, prognostic, and management implications of this interplay.
  • To explore the utility of conventional and novel diagnostic tools.

Main Methods:

  • Literature review of studies examining ocular manifestations of cardiovascular diseases.
  • Analysis of systemic diseases with known ocular and cardiac involvement.
  • Discussion of diagnostic tools for assessing the eye-cardiovascular link.

Main Results:

  • Hypertension and diabetes cause retinopathy; dyslipidemia presents with corneal arcus.
  • Autoimmune diseases (Graves', rheumatoid arthritis, sarcoidosis) manifest as proptosis, episcleritis, and scleritis.
  • Myasthenia gravis, Marfan syndrome, Wilson's disease, and Fabry disease show specific ocular and cardiac associations.

Conclusions:

  • Ocular assessment is crucial in cardiovascular examinations.
  • Recognizing ocular signs aids in early diagnosis and management of systemic and cardiovascular diseases.
  • Integrating advanced diagnostic tools can improve patient outcomes.

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