Related Experiment Video
Updated: Jul 21, 2025
06:58
An Application for Pairing with Wearable Devices to Monitor Personal Health Status
Published on: February 3, 2022
2.8K
Symptom Patterns in Young Adults with Cancer: An App-Based Study
Giulia Locatelli1, Alessandro Pasta2, Line Bentsen3
1School of Nursing, Midwifery and Paramedicine - Faculty of Health Sciences, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy; Faculty of Health Sciences, Australian Catholic University, Fitzroy Victoria, Melbourne, Australia.
Seminars in Oncology Nursing
|July 28, 2023
Summary
Young adults with cancer frequently experience mood disturbances and fatigue. A smartphone app revealed symptom clusters and showed that higher mood disturbance impacts activity levels, aiding tailored symptom management.
Area of Science:
- Oncology
- Digital Health
- Psycho-oncology
Background:
- Young adults with cancer face unique symptom burdens.
- Understanding symptom patterns is crucial for effective care.
- Smartphone technology offers novel data collection methods.
Purpose of the Study:
- Investigate symptom patterns in young adults with cancer.
- Explore symptom frequency, severity, and co-occurrence.
- Examine the relationship between symptoms and daily activities.
Main Methods:
- Utilized a smartphone app for data collection from 161 young adults with cancer.
- Employed descriptive statistics, k-means clustering, and association rule techniques.
- Applied mixed-effects logistic regression to analyze symptom-activity relationships.
Main Results:
- Mood disturbance and fatigue were the most reported and severe symptoms.
- Two patient clusters emerged based on overall symptom severity.
- Severe fatigue, appetite issues, and nausea frequently co-occurred.
- Increased mood disturbance correlated with reduced physical and social activity.
Conclusions:
- Smartphone-based symptom tracking provides valuable insights into young adult cancer patients' experiences.
- Identified distinct symptom clusters and co-occurrences.
- Demonstrated the impact of psychological symptoms on functional status.
Related Concept Videos
01:21Cancer Survival Analysis
386
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
386
02:53Adaptive Mechanisms in Cancer Cells
5.8K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
5.8K
02:18Cancer
48.8K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
48.8K
02:49Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
02:12What is Cancer?
10.8K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
10.8K
02:21Cancers Originate from Somatic Mutations in a Single Cell
12.0K
Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
12.0K