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Intracranial meningioma: a comparative pathologic study of 28 dogs
Veterinary Pathology
|July 1, 1986
Summary
This study identified intracranial meningiomas in 28 older dogs, with German Shepherds and mixed breeds most affected. Most tumors compressed the brain, causing neurologic signs, and can be compared to human and feline intracranial meningiomas.
Area of Science:
- Veterinary Neurology
- Comparative Pathology
- Canine Oncology
Background:
- Intracranial meningiomas are common primary tumors in the central nervous system of dogs.
- Understanding their characteristics is crucial for diagnosis and treatment.
Purpose of the Study:
- To characterize intracranial meningiomas in dogs.
- To compare canine intracranial meningiomas with those in humans and cats.
Main Methods:
- Histologic examination of 28 canine intracranial meningiomas.
- Gross and microscopic evaluation of tumor characteristics.
- Correlation of tumor findings with clinical signs.
Main Results:
- The average age of affected dogs was 11 years, with 83% being 10 years or older.
- Transitional and meningotheliomatous subtypes were most common.
- Neurologic signs were observed in 88% of dogs, with 27% showing direct brain invasion.
Conclusions:
- Intracranial meningiomas in dogs share similarities with human and feline counterparts.
- Age and breed predispositions are noted in canine intracranial meningiomas.
- Tumor location, histology, and brain invasion impact clinical presentation.