Related Experiment Video
Updated: Jul 21, 2025

Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases
Published on: August 23, 2024
MicroRNA (miR)-124: A Promising Therapeutic Gateway for Oncology
Karthik Gourishetti1,2, Vignesh Balaji Easwaran3, Youssef Mostakim1,2,4
1Biotherapeutics Laboratory, School of Medicine Columbia, University of South Carolina, Columbia, SC 29209, USA.
Abstract:
MicroRNA (miR) are a class of small non-coding RNA that are involved in post-transcriptional gene regulation. Altered expression of miR has been associated with several pathological conditions. MicroRNA-124 (miR-124) is an abundantly expressed miR in the brain as well as the thymus, lymph nodes, bone marrow, and peripheral blood mono-nuclear cells. It plays a key role in the regulation of the host immune system. Emerging studies show that dysregulated expression of miR-124 is a hallmark in several cancer types and it has been attributed to the progression of these malignancies. In this review, we present a comprehensive summary of the role of miR-124 as a promising therapeutic gateway in oncology.
Related Concept Videos
MicroRNAs
Microorganisms in Medicine and Therapeutics
Experimental RNAi

